dna-binding ELISA for activated Nrf2 transcription factor

品牌:Active Motif

期刊發表

 

產品說明:

TransAM Nrf2 Kits are DNA-binding ELISAs that provide everything needed to study NF-E2-related Factor 2 (Nrf2), including a positive control extract. The kit can be used with human, mouse and rat extracts.NF-E2-related factor 2 (Nrf2), also known as Nuclear Factor (erythroid-derived 2)-like 2 (NFE2L2) is a critical transcription factor in oxidative stress signaling. Nrf2 is a basic leucine zipper transcription factor that binds to the antioxidant responsive element (ARE) and may serve as a master regulator in cellular defense pathways in protecting a wide variety of tissues from various toxic exposure. Nrf2 is retained in the cytoplasm under normal conditions by interaction with the inhibitor KEAP1, but following oxidative stress Nrf is released from the inhibitor and translocates to the nucleas for activation of ARE-mediated gene expression. The ARE Respone Element is also available as a pre-cloned transfection ready luciferase reporter vector on the LightSwitch™ Reporter System page under Synthetic Response Element Collection.

 

應用:

  • ELISA assay

 

原廠連結:

https://www.activemotif.com/catalog/517/transam-nrf2

TransAM® Nrf2

  • 貨號

    品名

    包裝

    AMF50296

    TransAM® Nrf2

    1 x 96 rxns

    AMF50796

    TransAM® Nrf2

    5 x 96 rxns

Tel:02-222-33-900
Fax:02-222-33-980
23586新北市中和區中正路928號4樓
4F., No.928, Zhongzheng Rd., Zhonghe Dist., New Taipei City 235, Taiwan (R.O.C.)
Email:smt@star-moon.com.tw
© 2016 by STARMOONTECH.